Drugs A - Z

Trimethoprim Oral tablet

It is used to treat certain kinds of bacterial infections

Generic Name: trimethoprim  |  Brand Name: Proloprim

Brand Names: Primsol, Proloprim, Trimpex

What is this medicine?

TRIMETHOPRIM (trye METH oh prim) is an antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • kidney disease
  • liver disease
  • poor nutrition
  • an unusual or allergic reaction to trimethoprim, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not skip doses or stop your medicine early even if you feel better. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • dofetilide

This medicine may also interact with the following medications:

  • ACE inhibitors like benazepril, enalapril, lisinopril, moexipril, quinapril, ramipril, and others
  • dapsone
  • digoxin
  • fluorouracil
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • phenytoin
  • procainamide
  • pyrimethamine
  • some diuretics
  • trimetrexate
  • warfarin

What should I watch for while using this medicine?

Visit your doctor or health care professional as directed. Tell your doctor if your symptoms do not improve.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use a sunscreen. Do not use sun lamps or tanning beds/booths.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • fast or irregular heartbeat, chest pain
  • fever or chills, sore throat
  • bluish fingernails or lips
  • difficulty breathing
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • unusual bleeding or bruising
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome):

  • aches or pains
  • changes in taste
  • diarrhea
  • headache
  • nausea, vomiting
  • stomach pain

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light and moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: September 02, 2009
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