Drugs A - Z

Triamterene Oral capsule

It helps you make more urine and to lose excess water from your body

Generic Name: triamterene  |  Brand Name: Dyrenium

Brand Names: Dyrenium

There is an FDA Alert for this drug. Click here to view it.

  • Hyperkalemia (i.e., serum potassium concentrations ≥5.5 mEq/L) may occur with all potassium-sparing agents, including triamterene. More likely to occur in patients with renal impairment and diabetes (even without evidence of renal impairment), and in geriatric or severely ill patients or those receiving prolonged therapy with large doses.
  • Uncorrected hyperkalemia may be fatal; monitor serum potassium concentrations at frequent intervals especially during initial therapy, after dosage adjustment, or in patients with concurrent illness that may affect renal function.

What is this medicine?

TRIAMTERENE (trye AM ter een) is a diuretic. It helps you make more urine and to lose excess water from your body. This medicine is used to treat edema or swelling from heart, kidney, or liver disease. It is also used to treat patients who make too much aldosterone or have low potassium.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • high blood level of potassium
  • kidney disease or trouble making urine
  • liver disease
  • an unusual or allergic reaction to triamterene, other diuretics, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine after a meal to reduce stomach upset. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • eplerenone

This medicine may also interact with the following medications:

  • diuretics
  • lithium
  • medicines for diabetes that are taken by mouth
  • medicines for blood pressure, like ACE inhibitors
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • penicillin G potassium
  • potassium products like salt substitutes or supplements
  • skeletal muscle relaxants, like tubocurarine

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be, and when you should contact him or her.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

If you are diabetic, this medicine may increase your blood sugar levels. Check with your doctor or health care professional before you change the dose of your diabetic medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
  • black or tarry stools
  • lower back or side pain
  • muscle pain or cramps
  • numbness, tingling in hands or feet
  • trouble breathing
  • trouble passing urine
  • unusual bleeding
  • unusually weak or tired
  • yellowing of the skin or eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • headache
  • nausea, vomiting

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: September 03, 2009
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement
Advertisement