Drugs A - Z

Thrombin (Bovine) Medicated topical sponge

It stops bleeding during surgery.

Generic Name: thrombin topical  |  Brand Name: Thrombin-JMI

There is an FDA Alert for this drug. Click here to view it.

  • Use of topical thrombin (bovine) can stimulate antibody formation against bovine thrombin and/or bovine factor V, potentially resulting in severe hemorrhagic or thrombotic complications; rarely fatal. (See Antibody Formation under Cautions.)
  • Consult expert in coagulation disorders if patient exhibits abnormal coagulation test results, bleeding, or thrombosis. Do not readminister drug to patients with evidence of anti-bovine thrombin antibodies.

What is this medicine?

THROMBIN (THROM bin) stops bleeding during surgery.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • an unusual or allergic reaction to beef products, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is given by a health-care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Interactions are not expected.

What should I watch for while using this medicine?

Your condition will be closely monitored while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • high fever or fever lasting more than 24 hours

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • mild fever

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: September 03, 2009
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