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Sumatriptan Succinate Oral tablet

It is used to treat migraines with or without aura

Generic Name: sumatriptan  |  Brand Name: Imitrex

Brand Names: Sumatriptan Succinate, Imitrex

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

SUMATRIPTAN (soo ma TRIP tan) is used to treat migraines with or without aura. An aura is a strange feeling or visual disturbance that warns you of an attack. It is not used to prevent migraines.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bowel disease or colitis
  • diabetes
  • family history of heart disease
  • fast or irregular heart beat
  • heart or blood vessel disease, angina (chest pain), or previous heart attack
  • high blood pressure
  • high cholesterol
  • history of stroke, transient ischemic attacks (TIAs or mini-strokes), or intracranial bleeding
  • kidney or liver disease
  • overweight
  • poor circulation
  • postmenopausal or surgical removal of uterus and ovaries
  • Raynaud's disease
  • seizure disorder
  • an unusual or allergic reaction to sumatriptan, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. This medicine is taken at the first symptoms of a migraine. It is not for everyday use. If your migraine headache returns after one dose, you can take another dose as directed. You must leave at least 2 hours between doses, and do not take more than 100 mg as a single dose. Do not take more than 200 mg total in any 24 hour period. If there is no improvement at all after the first dose, do not take a second dose without talking to your doctor or health care professional. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply; this medicine is not for regular use.

What may interact with this medicine?

Do not take this medicine with any of the following medicines:
  • amphetamine or cocaine
  • dihydroergotamine, ergotamine, ergoloid mesylates, methysergide, or ergot-type medication - do not take within 24 hours of taking sumatriptan
  • feverfew
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate - do not take sumatriptan within 2 weeks of stopping MAOI therapy
  • other migraine medicines like almotriptan, eletriptan, naratriptan, rizatriptan, zolmitriptan - do not take within 24 hours of taking sumatriptan
  • tryptophan

This medicine may also interact with the following medications:

  • lithium
  • medicines for mental depression, anxiety or mood problems
  • medicines for weight loss such as dexfenfluramine, dextroamphetamine, fenfluramine, or sibutramine
  • St. John's wort

What should I watch for while using this medicine?

Only take this medicine for a migraine headache. Take it if you get warning symptoms or at the start of a migraine attack. It is not for regular use to prevent migraine attacks.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase drowsiness, dizziness and flushing. Avoid alcoholic drinks.

Smoking cigarettes may increase the risk of heart-related side effects from using this medicine.


Last Updated: February 23, 2009
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