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Sumatriptan Succinate Solution for injection

It is used to treat migraines with or without aura

Generic Name: sumatriptan injection

Brand Names: Imitrex Statdose Refill, Imitrex Statdose

There is an FDA Alert for this drug. Click here to view it.

REMS:

FDA approved a REMS for sumatriptan to ensure that the benefits of a drug outweigh the risks. The REMS may apply to one or more preparations of sumatriptan and consists of the following: medication guide. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

What is this medicine?

SUMATRIPTAN (soo ma TRIP tan) is used to treat migraines with or without aura. An aura is a strange feeling or visual disturbance that warns you of an attack. It is not used to prevent migraines.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bowel disease or colitis
  • diabetes
  • family history of heart disease
  • fast or irregular heart beat
  • heart or blood vessel disease, angina (chest pain), or previous heart attack
  • high blood pressure
  • high cholesterol
  • history of stroke, transient ischemic attacks (TIAs or mini-strokes), or intracranial bleeding
  • kidney or liver disease
  • overweight
  • poor circulation
  • postmenopausal or surgical removal of uterus and ovaries
  • Raynaud's disease
  • seizure disorder
  • an unusual or allergic reaction to sumatriptan, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection under the skin. Follow the directions on the prescription label. Only use this medicine at the first symptoms of a migraine. It is not for everyday use. If you are using an autoinjector, read the instruction leaflet carefully. A single injection is given just under the skin. Before you make an injection, clean and examine your skin. Do not inject at a place where the skin is damaged or infected. If your symptoms return you can use a second injection. If there is no improvement at all in your symptoms after the first injection, call your doctor or health care professional. Wait at least 1 hour between doses and do not use more than 6 mg as a single dose. Do not use more than 12 mg total in any 24 hour period. Do not use your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply; this medicine is not for regular use.

What may interact with this medicine?

Do not take this medicine with any of the following medicines:
  • amphetamine or cocaine
  • dihydroergotamine, ergotamine, ergoloid mesylates, methysergide, or ergot-type medication - do not take within 24 hours of taking sumatriptan.
  • feverfew
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate - do not take sumatriptan within 2 weeks of stopping MAOI therapy.
  • other migraine medicines like almotriptan, eletriptan, naratriptan, rizatriptan, zolmitriptan - do not take within 24 hours of taking sumatriptan.
  • tryptophan

This medicine may also interact with the following medications:

  • lithium
  • medicines for mental depression, anxiety or mood problems
  • medicines for weight loss such as dexfenfluramine, dextroamphetamine, fenfluramine, or sibutramine
  • St. John's wort

What should I watch for while using this medicine?

Only use this medicine for a migraine headache. Use it if you get warning symptoms or at the start of a migraine attack. This medicine is not for regular use to prevent migraine headaches.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase drowsiness, dizziness and flushing. Avoid alcoholic drinks.

Smoking cigarettes may increase the risk of heart-related side effects from using sumatriptan.


Last Updated: February 23, 2009
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