Drugs A - Z
Sertraline Hydrochloride Oral solution
Generic Name: sertraline
Brand Names: Zoloft
What is this medicine?SERTRALINE (SER tra leen) is used to treat depression. It may also be used to treat obsessive compulsive disorder, panic disorder, post-trauma stress, premenstrual dysphoric disorder (PMDD) or social anxiety.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- bipolar disorder or a family history of bipolar disorder
- heart disease
- liver disease
- receiving electroconvulsive therapy
- seizures (convulsions)
- suicidal thoughts, plans, or attempt by you or a family member
- an unusual or allergic reaction to sertraline, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Take this medicine by mouth. Follow the directions on the prescription label.
Before taking your dose, you need to dilute the solution in a beverage. Measure your medicine dose using the dropper in the bottle. Next, place the measured dose in at least 4 ounces (one-half cup) of water, ginger-ale, lemon-lime soda, lemonade or orange juice and mix. Do not mix in grapefruit juice or in any other liquids other than those listed.
Drink all of mixed liquid immediately. Do not mix the dose and store it for later. It must be taken right away. You may take this medicine with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 7 years for selected conditions, precautions do apply.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
- methylene blue (injected into a vein)
This medicine may also interact with the following medications:
- aspirin and aspirin-like medicines
- certain medicines for depression, anxiety, or psychotic disturbances
- certain medicines for migraine headaches like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
- certain medicines for seizures like carbamazepine, valproic acid, phenytoin
- medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
- medicines to control heart rhythm like flecainide or propafenone
- medicines for sleep
- NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
- supplements like St. John's wort, kava kava, valerian
What should I watch for while using this medicine?Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress. Because it may take several weeks to see the full effects of this medicine, it is important to continue your treatment as prescribed by your doctor.
Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine contains a high percentage of alcohol that may interact with medicines used to treat alcohol abuse, like Antabuse (disulfiram). You should not take these medicines together.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- black or bloody stools, blood in the urine or vomit
- fast, irregular heartbeat
- feeling faint or lightheaded, falls
- hallucination, loss of contact with reality
- suicidal thoughts or other mood changes
- unusual bleeding or bruising
- unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- change in appetite
- change in sex drive or performance
- indigestion, nausea
- increased sweating
Where should I keep my medicine?Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.