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Saxagliptin Oral tablet

It helps to control blood sugar

Generic Name: saxagliptin  |  Brand Name: Onglyza

Brand Names: Onglyza

What is this medicine?

SAXAGLIPTIN (SAX a glip tin) helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetic ketoacidosis
  • gallstones
  • high levels of triglyceride in the blood
  • history of alcohol abuse problem
  • history of pancreatitis
  • kidney disease
  • type 1 diabetes
  • an unusual or allergic reaction to saxagliptin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. Do not cut, crush, or chew this medicine. Take your dose at the same time each day. Do not take more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • gatifloxacin

This medicine may also interact with the following medications:

  • alcohol
  • atazanavir
  • clarithromycin
  • indinavir
  • insulin
  • itraconazole
  • ketoconazole
  • nefazodone
  • nelfinavir
  • ritonavir
  • saquinavir
  • sulfonylureas like glimepiride, glipizide, glyburide
  • telithromycin

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol.

If you have symptoms of low blood sugar, eat or drink something containing sugar at once, and contact your doctor or health care professional. Make sure family members know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar like seizures or unconsciousness. They must get medical help at once.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • confusion
  • fever or chills, cough, sore throat, pain or difficulty passing urine
  • low blood sugar (ask your doctor or healthcare professional for a list of these symptoms)
  • pain in the lower back
  • swelling of the ankles, feet, hands
  • unusual stomach upset or pain
  • unusually weak or tired
  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • nausea


Last Updated: December 28, 2011
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