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Risperidone Solution for injection

It is used to treat schizophrenia and bipolar disorder

Generic Name: risperidone  |  Brand Name: Risperdal

Brand Names: Risperdal, Risperdal M-Tab, Risperdal Consta

There is an FDA Alert for this drug. Click here to view it.

Special Alerts:

[Posted 06/13/2011] ISSUE: FDA notified healthcare professionals and the public of medication error reports in which patients were given risperidone (Risperdal) instead of ropinirole (Requip) and vice versa. In some cases, patients who took the wrong medication needed to be hospitalized.

The FDA determined that the factors contributing to the confusion between the two products include:

  • Similarities of both the brand (proprietary) and generic (established) names
  • Similarities of the container labels and carton packaging
  • Illegible handwriting on prescriptions
  • Overlapping product characteristics, such as the drug strengths, dosage forms, and dosing intervals.

BACKGROUND: Risperidone (Risperdal) is an antipsychotic medication used to treat mental illnesses including schizophrenia, bipolar disorder, and irritability associated with autistic disorder. Ropinirole (Requip) is a dopamine agonist used in the treatment of Parkinson’s disease and Restless Legs Syndrome.

RECOMMENDATION: Healthcare Professionals are reminded to clearly print or spell out the medication name on prescriptions and make certain their patients know the name of their prescribed medication and their reason for taking it. For more information visit the FDA website at: [Web] and [Web].

[Posted 02/22/2011] ISSUE: FDA notified healthcare professionals that the Pregnancy section of drug labels for the entire class of antipsychotic drugs has been updated. The new drug labels now contain more and consistent information about the potential risk for abnormal muscle movements (extrapyramidal signs or EPS) and withdrawal symptoms in newborns whose mothers were treated with these drugs during the third trimester of pregnancy.

The symptoms of EPS and withdrawal in newborns may include agitation, abnormally increased or decreased muscle tone, tremor, sleepiness, severe difficulty breathing, and difficulty in feeding. In some newborns, the symptoms subside within hours or days and do not require specific treatment; other newborns may require longer hospital stays.

BACKGROUND: Antipsychotic drugs are used to treat symptoms of psychiatric disorders such as schizophrenia and bipolar disorder.

RECOMMENDATION: Healthcare professionals should be aware of the effects of antipsychotic medications on newborns when the medications are used during pregnancy. Patients should not stop taking these medications if they become pregnant without talking to their healthcare professional, as abruptly stopping antipsychotic medications can cause significant complications for treatment. For more information visit the FDA website at: [Web] and [Web].

What is this medicine?

RISPERIDONE (ris PER i done) is used to treat schizophrenia and bipolar disorder. Bipolar disorder is also known as manic-depression.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • blood disorder or disease
  • dementia
  • diabetes or a family history of diabetes
  • difficulty swallowing
  • heart disease or previous heart attack
  • history of brain tumor or head injury
  • history of breast cancer
  • irregular heartbeat or low blood pressure
  • kidney disease
  • liver disease
  • Parkinson's disease
  • seizures
  • an unusual or allergic reaction to risperidone, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a muscle. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

Try to keep any appointments for your injections. Usually, this medicine is given every 2 weeks. Contact your health care provider for instructions if you miss an appointment.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • cisapride
  • droperidol
  • sparfloxacin

This medicine may also interact with the following medications:

  • arsenic trioxide
  • carbamazepine
  • certain medicines for the hormonal treatment of cancer
  • certain quinolone antibiotics like gatifloxacin, levofloxacin, moxifloxacin
  • clarithromycin
  • levodopa and other medications for Parkinson's disease
  • medicines for high blood pressure
  • medicines for irregular heartbeats
  • medicines for seizures
  • medicines for sleep or sedation
  • other medicines for mental anxiety, depression or psychotic disturbances
  • pentamidine
  • prescription pain medications
  • rifampin
  • ritonavir

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks.

Do not treat yourself for colds, diarrhea or allergies. Ask your doctor or health care professional for advice, some nonprescription medicines may increase possible side effects.

This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • aching muscles and joints
  • confusion
  • fast or irregular heartbeat
  • feeling faint, lightheaded, falls
  • fever or chills, sore throat
  • increased thirst or hunger
  • increased urination
  • lower belly pain
  • problems with balance, walking
  • stiffness, spasms, trembling
  • uncontrollable head, mouth, neck, arm, or leg movements
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • change in sex drive or performance
  • difficulty sleeping
  • drowsiness or dizziness
  • increase or decrease in saliva
  • nausea, vomiting
  • weight gain

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: May 07, 2013
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