Drugs A - Z

Risedronate Sodium Oral tablet, weekly

It helps to make normal healthy bone and to slow bone loss in people with osteoporosis

Generic Name: risedronate

Brand Names: Atelvia, Actonel

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

RISEDRONATE (ris ED roe nate) slows calcium loss from the bone. It helps to make normal healthy bone and to slow bone loss in people with osteoporosis.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • esophageal, stomach, or intestine problems, like acid reflux or GERD
  • dental disease
  • kidney disease
  • low blood calcium
  • problems sitting or standing for 30 minutes
  • trouble swallowing
  • an unusual or allergic reaction to risedronate, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

You must take this medicine exactly as directed or you will lower the amount of the medicine that you absorb into your body or you may cause yourself harm. Take this medicine by mouth after breakfast with a glass of water. Do not take this medicine before breakfast. Swallow the tablet with a full glass (6 to 8 ounces) of plain water. Do not take this medicine with any other drink. Do not chew, crush, or let the tablet dissolve in your mouth. Stand or sit up for at least 30 minutes after you take this medicine; do not lie down. Take this medicine on the same day every week. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take the dose on the morning after you remember. Then take your next dose on your regular day of the week. Never take 2 tablets on the same day. Do not take double or extra doses.

What may interact with this medicine?

  • aluminum hydroxide
  • antacids
  • aspirin
  • calcium supplements
  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • iron supplements
  • magnesium supplements
  • stomach acid blockers like cimetidine, famotidine, ranitidine, or omeprazole
  • vitamins with minerals

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular check ups. It may be some time before you see the benefit from this medicine. Do not stop taking your medicine unless your doctor tells you to. Your doctor may order blood tests or other tests to see how you are doing.

You should make sure that you get enough calcium and vitamin D while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.

Some people who take this medicine have severe bone, joint, and/or muscle pain. This medicine may also increase your risk for a broken thigh bone. Tell your doctor right away if you have pain in your upper leg or groin. Tell your doctor if you have any pain that does not go away or that gets worse.


Last Updated: June 18, 2012
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement