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Regorafenib Oral tablet

It targets specific proteins within cancer cells and stops the cancer cells from growing

Generic Name:

What is this medicine?

REGORAFENIB (RE goe RAF e nib) is a chemotherapy drug. It targets specific proteins within cancer cells and stops the cancer cells from growing. This medicine is used to treat colorectal cancer. It is also used to treat specific digestive tract tumors called GISTs.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

-bleeding disorders
-heart disease
-high blood pressure
-liver disease
-recent surgery
-an unusual or allergic reaction to regorafenib, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not take it more often than directed. Take this medicine with food. Do not take with grapefruit juice. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

This medicine may interact with the following:

-carbamazepine
-irinotecan
-itraconazole
-ketoconazole
-phenobarbital
-phenytoin
-posaconazole
-rifampin
-St. John's Wort
-telithromycin
-voriconazole
-warfarin

What should I watch for while using this medicine?

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

You may need blood work done while you are taking this medicine.

Do not become pregnant while taking this medicine or for 2 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 2 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.

If you are going to have surgery or any other procedures, tell your doctor you are taking this medicine.

Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.


Last Updated: February 26, 2013
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