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Rabeprazole Sodium Oral tablet, delayed-release

It prevents the production of acid in the stomach

Generic Name: rabeprazole

Brand Names: Aciphex

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

RABEPRAZOLE (ra BE pray zole) prevents the production of acid in the stomach. It is used to treat gastroesophageal reflux disease (GERD), certain ulcers, inflammation of the esophagus, and Zollinger-Ellison Syndrome.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • liver disease
  • low levels of magnesium in the blood
  • an unusual or allergic reaction to rabeprazole, esomeprazole, omeprazole, lansoprazole, pantoprazole, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Swallow the tablets whole with a drink of water. Follow the directions on the prescription label. Do not crush, break, or chew. You may take this medicine with or without food. Take your medicine at regular intervals. Do not take more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • atazanavir
  • nelfinavir

This medicine may also interact with the following medications:

  • amiophylline or theophylline
  • amoxicillin
  • ampicillin
  • clarithromycin
  • cyclosporine
  • diazepam
  • digoxin
  • diuretics
  • iron salts
  • itraconazole, ketoconazole, voriconazole, or other prescription medicines for fungus or yeast infections
  • methotrexate
  • phenytoin
  • warfarin

What should I watch for while using this medicine?

It can take several days before your stomach pain gets better. Check with your doctor or health care professional if your condition does not start to get better, or if it gets worse.

You may need blood work done while you are taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • bone, muscle or joint pain
  • breathing problems
  • chest pain or chest tightness
  • dark yellow or brown urine
  • dizziness
  • fast, irregular heartbeat
  • feeling faint or lightheaded
  • fever or sore throat
  • muscle spasm
  • palpitations
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • seizures
  • tremors
  • unusual bleeding or bruising
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • constipation
  • diarrhea
  • dry mouth
  • headache
  • nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: April 05, 2013
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