Drugs A - Z
Quetiapine Fumarate Oral tablet, extended release
Generic Name: quetiapine | Brand Name: Seroquel
What is this medicine?QUETIAPINE (kwe TYE a peen) is an antipsychotic. It is used to treat schizophrenia and bipolar disorder, also known as manic-depression. It is also used to treat major depression in combination with antidepressants.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- brain tumor or head injury
- breast cancer
- difficulty swallowing
- heart disease
- kidney disease
- liver disease
- low blood counts, like low white cell, platelet, or red cell counts
- low blood pressure or dizziness when standing up
- Parkinson's disease
- previous heart attack
- suicidal thoughts, plans, or attempt by you or a family member
- thyroid disease
- an unusual or allergic reaction to quetiapine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. Take this medicine on an empty stomach or with a light meal. Do not take this medicine with a full heavy meal. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
- antifungal medicines like fluconazole, itraconazole, ketoconazole
- antiviral medicines for HIV or AIDS
- medicines for depression, anxiety, or psychotic disturbances
- medicines for high blood pressure
- medicines for Parkinson's disease
- medicines for seizures like carbamazepine, phenobarbital, phenytoin
- steroid medicines like prednisone or cortisone
What should I watch for while using this medicine?Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine.
Your health care provider may suggest that you have your eyes examined prior to starting this medicine, and every 6 months thereafter.
If you have been taking this medicine regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose or your symptoms may get worse. Ask your doctor or health care professional for advice.
Patients and their families should watch out for depression or thoughts of suicide that get worse. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of antidepressant treatment or after a change in dose, call your health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Do not treat yourself for colds, diarrhea or allergies. Ask your doctor or health care professional for advice, some ingredients may increase possible side effects.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- difficulty swallowing
- fast, irregular heartbeat
- fever or chills, sore throat
- increased hunger or thirst
- increased urination
- problems with balance, talking, walking
- stiff muscles
- suicidal thoughts or other mood changes
- uncontrollable head, mouth, neck, arm, or leg movements
- unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- change in sex drive or performance
- dry mouth
- sexual difficulties
- stomach upset
- weight gain
Where should I keep my medicine?Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.