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Progesterone Vaginal gel

This medicine is used to help women who are going through an Assisted Reproductive Technology (ART) ... more

Generic Name: progesterone vaginal

Brand Names: Endometrin, FIRST-Progesterone VGS 100, FIRST-Progesterone VGS 200, FIRST-Progesterone VGS 50, FIRST-Progesterone VGS 25, Prochieve, Crinone, FIRST-Progesterone VGS 400

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. This medicine is used to help women who are going through an Assisted Reproductive Technology (ART) treatment program to become pregnant. It is also used to treat secondary amenorrhea. This is when a woman stops getting menstrual periods due to low levels of progesterone.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • blood vessel disease, blood clotting disorder, or suffered a stroke
  • breast, cervical or vaginal cancer
  • heart disease
  • kidney disease
  • liver disease
  • miscarriage or abortion
  • vaginal bleeding
  • an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for use in the vagina. Do not take by mouth. Follow the directions on the prescription label. Use the applicator exactly as directed. Do not use more often than prescribed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other vaginal products without asking your doctor or health care professional.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

If your doctor or health care professional instructs you to use any other medicines in the vagina while you are using this medicine, you should separate the doses by at least 6 hours.

You may notice a white discharge of medicine while using this medicine. This is normal. If it becomes bothersome, contact your doctor or health care professional.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • abnormal vaginal bleeding
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breast tissue changes or discharge
  • changes in vision
  • chest pain
  • confusion, trouble speaking or understanding
  • dark urine
  • general ill feeling or flu-like symptoms
  • light-colored stools
  • loss of appetite, nausea
  • pain, swelling, warmth in the leg
  • right upper belly pain
  • severe headaches
  • shortness of breath
  • sudden numbness or weakness of the face, arm or leg
  • trouble walking, dizziness, loss of balance or coordination
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain
  • depressed mood or mood swings
  • increased appetite
  • fluid retention and swelling
  • nausea, vomiting
  • stomach cramps or bloating

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: July 20, 2009
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