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Pramipexole Dihydrochloride Oral tablet, extended release

It is used to treat symptoms of Parkinson's disease.

Generic Name: Mirapex ER

What is this medicine?

PRAMIPEXOLE (pra mi PEX ole) is used to treat symptoms of Parkinson's disease.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • dizzy or fainting spells
  • heart disease
  • kidney disease
  • low blood pressure
  • sleeping problems
  • an unusual or allergic reaction to pramipexole, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, skip the dose you missed. Take the next dose at your regular time. Do not take double or extra doses.

What may interact with this medicine?

  • amantadine
  • cimetidine
  • diltiazem
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • metoclopramide
  • quinidine or quinine
  • ranitidine
  • triamterene
  • verapamil

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. It may be several weeks or months before you feel the full effect of this medicine. Continue to take your medicine on a regular schedule.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. If you find that you have sudden feelings of wanting to sleep during normal activities, like cooking, watching television, or while driving or riding in a car, you should contact your health care professional.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

There have been reports of increased sexual urges or other strong urges such as gambling while taking some medicines for Parkinson's disease. If you experience any of these urges while taking this medicine, you should report it to your health care provider as soon as possible.

You should check your skin often for changes to moles and new growths while taking this medicine. Call your doctor if you notice any of these changes.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • changes in vision
  • confusion
  • fainting spells
  • falling asleep during normal activities like driving
  • hallucination, loss of contact with reality
  • mood changes
  • muscle pain or severe muscle weakness
  • uncontrollable movements of the arms, face, hands, head, mouth, shoulders, or upper body

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • constipation
  • frequent urination
  • mild weakness
  • nausea


Last Updated: April 06, 2010
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