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Pramipexole Dihydrochloride Oral tablet

It is used to treat symptoms of Parkinson's disease

Generic Name: pramipexole

Brand Names: Mirapex ER, Mirapex

What is this medicine?

PRAMIPEXOLE (pra mi PEX ole) is used to treat symptoms of Parkinson's disease. It is also used to treat Restless Legs Syndrome.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • dizzy or fainting spells
  • heart disease
  • kidney disease
  • low blood pressure
  • sleeping problems
  • an unusual or allergic reaction to pramipexole, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • amantadine
  • cimetidine
  • diltiazem
  • medicines for mental problems or psychotic disturbances
  • medicines for sleep
  • metoclopramide
  • quinidine or quinine
  • ranitidine
  • triamterene
  • verapamil

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. It may be several weeks or months before you feel the full effect of this medicine. Continue to take your medicine on a regular schedule.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. If you find that you have sudden feelings of wanting to sleep during normal activities, like cooking, watching television, or while driving or riding in a car, you should contact your health care professional.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

There have been reports of increased sexual urges or other strong urges such as gambling while taking some medicines for Parkinson's disease. If you experience any of these urges while taking this medicine, you should report it to your health care provider as soon as possible.

You should check your skin often for changes to moles and new growths while taking this medicine. Call your doctor if you notice any of these changes.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • confusion
  • double vision or other vision problems
  • fainting spells
  • falling asleep during normal activities like driving
  • hallucination, loss of contact with reality
  • mental changes
  • muscle pain or severe muscle weakness
  • uncontrollable movements of the arms, face, hands, head, mouth, shoulders, or upper body

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • frequent urination
  • mild weakness
  • nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: April 06, 2010
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