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Phenytoin Sodium Solution for injection

It is used to control seizures in certain types of epilepsy

Generic Name: phenytoin  |  Brand Name: Dilantin

Brand Names: Phenytoin Sodium, Prompt, Dilantin Kapseals, Dilantin, Di-Phen, Dilantin-125, Dilantin Infatabs, Phenytoin Sodium, Phenytoin Sodium, Extended Release, Phenytek

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

PHENYTOIN (FEN i toyn) is used to control seizures in certain types of epilepsy. It is also used to prevent seizures during or after surgery.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • an alcohol abuse problem
  • Asian ancestry
  • diabetes
  • heart problems
  • liver disease
  • low blood pressure
  • suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
  • an unusual or allergic reaction to phenytoin, hydantoin or other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • delavirdine

This medicine may also interact with the following medications:

  • alcohol
  • aspirin and aspirin-like medicines
  • barbiturates, like phenobarbital
  • carbamazepine
  • chloramphenicol
  • chlordiazepoxide
  • cimetidine
  • diazepam
  • digoxin
  • disulfiram
  • doxycycline
  • ethosuximide
  • female hormones, like estrogens and birth control pills
  • furosemide
  • halothane
  • isoniazid
  • medicines for mental depression, anxiety or other mood problems
  • methylphenidate
  • molindone
  • other medicines for seizures
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • phenylbutazone
  • quinidine
  • reserpine
  • rifampin
  • steroid medicines like prednisone or cortisone
  • sulfonamides like sulfamethoxazole, sulfasalazine
  • tolbutamide
  • trazodone
  • valproic acid
  • warfarin

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

The use of this medicine may increase the chance of suicidal thoughts or actions. Pay special attention to how you are responding while on this medicine. Any worsening of mood, or thoughts of suicide or dying should be reported to your health care professional right away.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • changes in vision
  • chest pain or tightness
  • confusion
  • dark yellow or brown urine
  • fast or irregular heartbeat
  • fever, sore throat
  • headache
  • loss of seizure control
  • poor control of body movements or difficulty walking
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • unusual bleeding or bruising, pinpoint red spots on skin
  • vomiting
  • worsening of mood, thoughts or actions of suicide or dying
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • difficulty sleeping
  • excessive hair growth on the face or body
  • nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: July 21, 2009
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