Drugs A - Z

Paliperidone palmitate Suspension for injection

It injection is used to treat schizophrenia.

Generic Name: paliperidone injection

Brand Names: Invega Sustenna

What is this medicine?

PALIPERIDONE (pal ee PER i done) injection is used to treat schizophrenia.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • chronic constipation or diarrhea
  • dementia
  • diabetes or family history of diabetes
  • history of stroke
  • irregular heartbeat or low blood pressure
  • kidney disease
  • liver disease
  • stomach problems like adhesions, bowel disease, short gut, trouble swallowing
  • an unusual or allergic reaction to paliperidone, risperidone, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a muscle. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

Try to keep all appointments for your injections. Usually, this medicine is given every 4 weeks. Contact your health care provider for instructions if you miss an appointment.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • bepridil
  • cisapride
  • droperidol
  • grepafloxacin
  • halofantrine
  • levomethadyl
  • pimozide
  • sertindole
  • some phenothiazines like chlorpromazine, mesoridazine, thioridazine
  • sparfloxacin

This medicine may also interact with the following medications:

  • abarelix
  • alcohol
  • alfuzosin
  • antibiotics like clarithromycin, erythromycin, gemifloxacin, levofloxacin
  • carbamazepine
  • chloroquine
  • cyclobenzaprine
  • daunorubicin, doxorubicin
  • dolasetron
  • levodopa and other medications for Parkinson's disease
  • lithium
  • local anesthetics
  • medicines for anxiety, depression or psychotic disturbances
  • medicines for blood pressure
  • medicines for irregular heartbeat
  • medicines for sleep
  • medicines for treating seizures
  • octreotide
  • ondansetron
  • other medicines for schizophrenia
  • pentamidine
  • prescription pain medications
  • rifampin
  • St. John's Wort
  • tramadol
  • vorinostat

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. It may be several weeks before you see the full effects. Do not stop this medicine except on the advice of your doctor or health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • change in blood sugar
  • changes in vision
  • confusion
  • dark urine
  • fast or irregular heartbeat
  • feeling faint or lightheaded, falls
  • fever or chills, sore throat
  • increased thirst or hunger
  • inner restlessness, unable to keep still
  • men: prolonged or painful erection
  • muscle pain, stiffness
  • redness or swelling at the injection site
  • trouble passing urine or change in the amount of urine
  • unusual decrease in sweating
  • unusual movements, spasms, tremor

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • change in sex drive or performance
  • cough
  • drowsiness
  • dry mouth
  • headache


Last Updated: May 07, 2013
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
 

Paliperidone injection

 
Advertisement
Advertisement