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Palifermin (E. coli) Solution for injection

It is used to treat and to prevent severe mouth sores in patients with blood-related cancers receivi... more

Generic Name: palifermin  |  Brand Name: Kepivance

Brand Names: Kepivance

What is this medicine?

PALIFERMIN (pal ee FER min) is a man-made form of a natural growth factor. It is used to treat and to prevent severe mouth sores in patients with blood-related cancers receiving chemotherapy and/or radiation therapy.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • an unusual or allergic reaction to palifermin, E. coli protein, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

-certain medicines that treat or prevent blood clots like heparin, enoxaparin, and dalteparin
This medicine may also interact with the following medications:

-medicines to treat cancer

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Do not use this medicine if you have a cancer that is not a blood-related cancer. This medicine may cause other cancers to grow.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • burning, tingling in or around the mouth
  • fever
  • high blood pressure
  • joint pain
  • swelling of the hands or feet
  • thickening of the tongue

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • change in tongue color
  • changes in taste
  • stomach upset

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: June 06, 2013
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