Drugs A - Z

Omeprazole Gastro-resistant tablet

It prevents the production of acid in the stomach

Generic Name: omeprazole

Brand Names: Prilosec OTC, Prilosec

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

OMEPRAZOLE (oh ME pray zol) prevents the production of acid in the stomach. It is used to treat the symptoms of heartburn. You can buy this medicine without a prescription. This product is not for long-term use, unless otherwise directed by your doctor or health care professional.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • black or bloody stools
  • chest pain
  • difficulty swallowing
  • have had heartburn for over 3 months
  • have heartburn with dizziness, lightheadedness or sweating
  • liver disease
  • stomach pain
  • unexplained weight loss
  • vomiting with blood
  • wheezing
  • an unusual or allergic reaction to omeprazole, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the product label. If you are taking this medicine without a prescription, take one tablet every day. Do not use for longer than 14 days or repeat a course of treatment more often than every 4 months unless directed by a doctor or healthcare professional. Take your dose at regular intervals every 24 hours. Swallow the tablet whole with a drink of water. Do not crush, break or chew. This medicine works best if taken on an empty stomach 30 minutes before breakfast. If you are using this medicine with the prescription of your doctor or healthcare professional, follow the directions you were given. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • atazanavir
  • clopidogrel
  • nelfinavir

This medicine may also interact with the following medications:

  • ampicillin
  • certain medicines for anxiety or sleep
  • certain medicines that treat or prevent blood clots like warfarin
  • cyclosporine
  • diazepam
  • digoxin
  • disulfiram
  • iron salts
  • phenytoin
  • prescription medicine for fungal or yeast infection like itraconazole, ketoconazole, voriconazole
  • saquinavir
  • tacrolimus

What should I watch for while using this medicine?

It can take several days before your heartburn gets better. Check with your doctor or health care professional if your condition does not start to get better, or if it gets worse.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

Do not treat yourself for heartburn with this medicine for more than 14 days in a row. You should only use this medicine for a 2-week treatment period once every 4 months. If your symptoms return shortly after your therapy is complete, or within the 4 month time frame, call your doctor or health care professional.


Last Updated: September 17, 2012
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement