Drugs A - Z

Omalizumab (Hamster) Solution for injection

It is used to help treat allergic asthma and other allergies

Generic Name: omalizumab  |  Brand Name: Xolair

Brand Names: Xolair

There is an FDA Alert for this drug. Click here to view it.

  • Anaphylaxis (e.g., bronchospasm, hypotension, syncope, urticaria, angioedema of throat or tongue) reported.
  • Anaphylaxis can occur after the first or second dose of omalizumab, but may occur after >1 year of therapy. Monitor patient for an appropriate period of time following administration. (See Cautions: Medical Personnel and Facilities and see Sensitivity Reactions.)
  • Administer omalizumab in a setting prepared to manage potentially life-threatening anaphylaxis; clinicians administering the drug should be familiar with management of anaphylaxis.
  • Inform patient of the signs and symptoms of anaphylaxis and instruct patient to obtain immediate medical care should symptoms develop.

REMS:

FDA approved a REMS for omalizumab to ensure that the benefits of a drug outweigh the risks. The REMS may apply to one or more preparations of omalizumab and consists of the following: medication guide. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

What is this medicine?

OMALIZUMAB (oh mah lye ZOO mab) is used to help treat allergic asthma and other allergies. It may be given with other treatments for these conditions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • lymphoma or other cancer
  • an unusual or allergic reaction to omalizumab, hamster proteins, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection under the skin. It is given by a health care professional in a hospital or clinic setting.

A special MedGuide will be given to you with each injection. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children for selected conditions, precautions do apply.

What if I miss a dose?

It is important not to miss your dose. This medicine is usually given every 2 to 4 weeks. Call your doctor or health care professional if you are unable to keep an appointment.

What may interact with this medicine?

Interactions are not expected.

What should I watch for while using this medicine?

After receiving each injection, you will be monitored for a short time in your doctor's office or clinic.

Improvement of your asthma or allergies will not be immediate. Improvements will occur gradually.

You will have regular blood tests to determine how often you will need this medicine.

Do not stop taking any of your other asthma or allergy treatments unless otherwise directed by your doctor.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • pain, tingling, numbness in the hands or feet
  • unusual bleeding or bruising

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • mild redness, itching, swelling, or bruising at the injection site
  • nausea

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: July 14, 2009
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement