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Olanzapine Oral disintegrating tablet

It is used to treat schizophrenia, psychotic disorders, and bipolar disorder

Generic Name: olanzapine

Brand Names: Zyprexa Zydis, Zyprexa

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

OLANZAPINE (oh LAN za peen) is used to treat schizophrenia, psychotic disorders, and bipolar disorder. Bipolar disorder is also known as manic-depression.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • breast cancer or history or breast cancer
  • dementia
  • diabetes mellitus, high blood sugar or a family history of diabetes
  • difficulty swallowing
  • glaucoma
  • heart disease, irregular heartbeat, or previous heart attack
  • history of brain tumor or head injury
  • kidney or liver disease
  • low blood pressure or dizziness when standing up
  • Parkinson's disease
  • prostate trouble
  • seizures (convulsions)
  • suicidal thoughts, plans, or attempt by you or a family member
  • an unusual or allergic reaction to olanzapine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Leave the tablet in the foil package until you are ready to take it. Do not push the tablet through the blister pack. Peel open the package with dry hands and place the tablet on your tongue. The tablet will dissolve rapidly and be swallowed in your saliva. While you may take these tablets with food or water, it is not necessary to do so. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

A special MedGuide will be given to you by the pharmacist with each new prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 13 years for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • certain antibiotics like grepafloxacin and sparfloxacin
  • certain phenothiazines like chlorpromazine, mesoridazine, and thioridazine
  • cisapride
  • clozapine
  • droperidol
  • halofantrine
  • levomethadyl
  • pimozide

This medicine may also interact with the following medications:

  • carbamazepine
  • charcoal
  • fluvoxamine
  • levodopa and other medicines for Parkinson's disease
  • medicines for diabetes
  • medicines for high blood pressure
  • medicines for mental depression, anxiety, other mood disorders, or sleeping problems
  • omeprazole
  • rifampin
  • ritonavir
  • tobacco from cigarettes


Last Updated: May 07, 2013
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