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Nitroglycerin Sublingual tablet

It relaxes blood vessels, increasing the blood and oxygen supply to your heart

Generic Name: nitroglycerin  |  Brand Name: Nitro-Time

What is this medicine?

NITROGLYCERIN (nye troe GLI ser in) is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. This medicine is used to relieve chest pain caused by angina. It is also used to prevent chest pain before activities like climbing stairs, going outdoors in cold weather, or sexual activity.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • head injury, recent stroke, or bleeding in the brain
  • liver disease
  • previous heart attack
  • an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth as needed. At the first sign of an angina attack (chest pain or tightness) place one tablet under your tongue. You can also take this medicine 5 to 10 minutes before an event likely to produce chest pain. Follow the directions on the prescription label. Let the tablet dissolve under the tongue. Do not swallow whole. Replace the dose if you accidentally swallow it. It will help if your mouth is not dry. Saliva around the tablet will help it to dissolve more quickly. Do not eat or drink, smoke or chew tobacco while a tablet is dissolving. If you are not better within 5 minutes after taking ONE dose of nitroglycerin, call 9-1-1 immediately to seek emergency medical care. Do not take more than 3 nitroglycerin tablets over 15 minutes.

If you take this medicine often to relieve symptoms of angina, your doctor or health care professional may provide you with different instructions to manage your symptoms. If symptoms do not go away after following these instructions, it is important to call 9-1-1 immediately. Do not take more than 3 nitroglycerin tablets over 15 minutes.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply. This medicine is only used as needed.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • certain migraine medicines like ergotamine and dihydroergotamine (DHE)
  • medicines used to treat erectile dysfunction like sildenafil, tadalafil, and vardenafil

This medicine may also interact with the following medications:

  • alteplase
  • aspirin
  • heparin
  • medicines for high blood pressure
  • medicines for mental depression
  • other medicines used to treat angina
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine


Last Updated: July 10, 2009
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