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Moxifloxacin Hydrochloride, Sodium Chloride Solution for injection

It is used to treat certain kinds of bacterial infections

Generic Name: moxifloxacin  |  Brand Name: Avelox

Brand Names: Avelox

There is an FDA Alert for this drug. Click here to view it.

  • Fluoroquinolones, including moxifloxacin, are associated with an increased risk of tendinitis and tendon rupture in all age groups. This risk is further increased in older adults (usually those >60 years of age), individuals receiving concomitant corticosteroids, and kidney, heart, or lung transplant recipients. (See Tendinopathy and Tendon Rupture under Cautions.)

REMS:

FDA approved a REMS for moxifloxacin to ensure that the benefits of a drug outweigh the risks. However, FDA later rescinded REMS requirements. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

What is this medicine?

MOXIFLOXACIN (mox i FLOX a sin) is a quinolone antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

-bone problems
-cerebral disease
-joint problems
-irregular heartbeat
-liver disease
-myasthenia gravis
-seizure disorder
-tendon problems
-an unusual or allergic reaction to moxifloxacin, other quinolone antibiotics, other medicines, foods, dyes, or preservatives
-pregnant or try to get pregnant
-breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is usually given by a health care provider in a hospital or clinic.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • arsenic trioxide
  • chloroquine
  • cisapride
  • droperidol
  • halofantrine
  • pentamidine
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • pimozide
  • some medications for irregular heart beat like amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine, procainamide, sotalol
  • ziprasidone

This medicine may also interact with the following medications:

  • erythromycin
  • medicines for depression, anxiety, or psychotic disturbances
  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • warfarin

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.

Do not treat diarrhea with over-the-counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if the diarrhea is severe and watery.

If you have diabetes, monitor your blood glucose carefully while on this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.


Last Updated: January 04, 2013
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