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Moxifloxacin Hydrochloride Oral tablet

It is used to treat certain kinds of bacterial infections

Generic Name: moxifloxacin

Brand Names: Avelox

There is an FDA Alert for this drug. Click here to view it.

  • Fluoroquinolones, including moxifloxacin, are associated with an increased risk of tendinitis and tendon rupture in all age groups. This risk is further increased in older adults (usually those >60 years of age), individuals receiving concomitant corticosteroids, and kidney, heart, or lung transplant recipients. (See Tendinopathy and Tendon Rupture under Cautions.)

REMS:

FDA approved a REMS for moxifloxacin to ensure that the benefits of a drug outweigh the risks. However, FDA later rescinded REMS requirements. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

What is this medicine?

MOXIFLOXACIN (mox i FLOX a sin) is a quinolone antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • cerebral disease
  • heart condition
  • liver disease
  • seizures disorder
  • an unusual or allergic reaction to moxifloxacin, other quinolone antibiotics, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. It can be taken with or without food. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. Do not skip doses or stop your medicine early.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • arsenic trioxide
  • chloroquine
  • cisapride
  • droperidol
  • halofantrine
  • pentamidine
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • pimozide
  • some medications for irregular heart rhythm like amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine, procainamide, sotalol
  • ziprasidone

This medicine may also interact with the following medications:

  • antacids
  • didanosine (ddI) buffered tablets or powder
  • erythromycin
  • medicines for inflammation like ibuprofen, naproxen
  • vitamins with iron or zinc
  • medicines for depression, anxiety, or psychotic disturbances
  • sucralfate
  • warfarin

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

If you have diabetes, monitor your blood glucose carefully while on this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Avoid antacids, aluminum, calcium, iron, magnesium, and zinc products for 4 hours before and 8 hours after taking a dose of this medicine.


Last Updated: January 04, 2013
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