Drugs A - Z
Morphine Sulfate Rectal suppository
Generic Name: morphine | Brand Name: Roxanol
What is this medicine?MORPHINE (MOR feen) is a pain reliever. It is used to treat moderate to severe pain.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- brain tumor
- drug abuse or addiction
- head injury
- heart disease
- if you frequently drink alcohol-containing drinks
- intestinal disease
- kidney disease or problems urinating
- liver disease
- lung disease, asthma, or breathing problems
- taken isocarboxazid, phenelzine, tranylcypromine, or selegiline in the past 2 weeks
- an unusual or allergic reaction to morphine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?This medicine is for rectal use only. Do not take by mouth. Wash your hands before and after use. Take off the foil wrapping. Wet the tip of the suppository with cold tap water to make it easier to use. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Apply gentle pressure to insert the suppository completely into the rectum, pointed end first. Hold buttocks together for a few seconds. Remain lying down for about 15 minutes to avoid having the suppository come out. Do not use more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
- barbiturates, like phenobarbital
- medicines for depression, anxiety, or psychotic disturbances
- medicines for sleep
- muscle relaxants
- naltrexone, naloxone
- narcotic medicines (opiates) for pain
What should I watch for while using this medicine?Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take morphine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
You may get drowsy or dizzy when you first start taking the medicine or change doses. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Stand or sit up slowly.
There are different types of narcotic medicines (opiates) for pain. If you take more than one type at the same time, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Your mouth may get dry. Drinking water, chewing sugarless gum, or sucking on hard candy may help. See your dentist every 6 months.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- change in the amount of urine
- fever, chills
- feeling faint or lightheaded
- red or sore at the injection site
- slow or fast heartbeat
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- dizzy, drowsy
- nausea, vomiting
- pinpoint pupils
Where should I keep my medicine?Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and is against the law.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze the medicine. Do not unwrap the medicine until you are ready to use it.
Throw away any unused medicine after the expiration date. Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.