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Morphine Sulfate Oral capsule, extended release

It is used to treat moderate to severe pain that lasts for more than a few days

Generic Name: morphine

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

MORPHINE (MOR feen) is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • brain tumor
  • drug abuse or addiction
  • head injury
  • heart disease
  • if you frequently drink alcohol-containing drinks
  • intestinal disease
  • kidney disease or problems urinating
  • kyphoscoliosis
  • liver disease
  • lung disease, asthma, or breathing problems
  • seizures
  • taken isocarboxazid, phenelzine, tranylcypromine, or selegiline in the past 2 weeks
  • an unusual or allergic reaction to morphine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Do not break, crush, or chew the capsules. Do not take a capsule that is not whole. A broken or crushed capsule can be very dangerous. You may get too much medicine. If the medicine upsets your stomach, take the medicine with food or milk. If you have problems swallowing the capsule, you may carefully open it and sprinkle the contents on a small amount of cold applesauce. Immediately swallow all of the applesauce. Do not save it for later. Do not chew the applesauce. Do not let the medicine dissolve in the applesauce. Rinse your mouth with a sip of water. None of the medicine should stay in your mouth. Swallow all of the medicine. Follow the directions on the prescription label. Take the medicine at the same time each day. Do not take more medicine than you are told to take.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

This medicine may also interact with the following medications:

  • alcohol
  • antihistamines
  • barbiturates, like phenobarbital
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • muscle relaxants
  • naltrexone, naloxone
  • narcotic medicines (opiates) for pain
  • rifampin
  • tramadol


Last Updated: August 24, 2012
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