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Modafinil Oral tablet

It is used to treat excessive sleepiness caused by certain sleep disorders

Generic Name: modafinil  |  Brand Name: Provigil

Brand Names: Provigil

There is an FDA Alert for this drug. Click here to view it.

REMS:

FDA approved a REMS for modafinil to ensure that the benefits of a drug outweigh the risks. The REMS may apply to one or more preparations of modafinil and consists of the following: medication guide and communication plan. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

What is this medicine?

MODAFINIL (moe DAF i nil) is used to treat excessive sleepiness caused by certain sleep disorders. This includes narcolepsy, sleep apnea, and shift work sleep disorder.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • history of depression, mania, or other mental disorder
  • kidney disease
  • liver disease
  • an unusual or allergic reaction to modafinil, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • amphetamine or dextroamphetamine
  • dexmethylphenidate or methylphenidate
  • medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
  • pemoline
  • procarbazine

This medicine may also interact with the following medications:

  • antifungal medicines like itraconazole or ketoconazole
  • barbiturates like phenobarbital
  • birth control pills or other hormone-containing birth control devices or implants
  • carbamazepine
  • cyclosporine
  • diazepam
  • medicines for depression, anxiety, or psychotic disturbances
  • phenytoin
  • propranolol
  • triazolam
  • warfarin

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. The full effects of this medicine may not be seen right away.

This medicine may affect your concentration, function, or may hide signs that you are tired. You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Alcohol can make you more dizzy and may interfere with your response to this medicine or your alertness. Avoid alcoholic drinks.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

It is unknown if the effects of this medicine will be increased by the use of caffeine. Caffeine is available in many foods, beverages, and medications. Ask your doctor if you should limit or change your intake of caffeine-containing products while on this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • anxiety
  • breathing problems
  • chest pain
  • fast, irregular heartbeat
  • hallucinations
  • increased blood pressure
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • sore throat, fever, or chills
  • suicidal thoughts or other mood changes
  • tremors
  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • nausea, diarrhea, or stomach upset
  • nervousness
  • trouble sleeping


Last Updated: November 30, 2010
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