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Midazolam Hydrochloride Oral syrup

It is used to cause relaxation or sleep before surgery and to block the memory of the procedure

Generic Name: midazolam

Brand Names: Midazolam Hydrochloride, Versed

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

MIDAZOLAM (MID ay zoe lam) is a benzodiazepine. It is used to cause relaxation or sleep before surgery and to block the memory of the procedure.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • an alcohol or drug abuse problem
  • bipolar disorder, depression, psychosis, or other mental health condition
  • glaucoma
  • heart disease
  • kidney disease
  • liver disease
  • lung or breathing disease, like asthma
  • seizures or a history of seizures
  • suicidal thoughts
  • an unusual or allergic reaction to midazolam, other benzodiazepines, cherries, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is given by a health-care professional in a hospital or clinic setting. It is not prescribed for use at home.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • certain antiviral medicines for HIV or AIDS
  • delavirdine
  • efavirenz
  • grapefruit juice
  • itraconazole
  • ketoconazole

This medicine may also interact with the following medications:

  • cimetidine
  • diltiazem
  • droperidol
  • general anesthetics
  • narcotic medicines for pain
  • rifampin, rifapentine, or rifabutin
  • secobarbital
  • some antibiotics like clarithromycin, erythromycin, and troleandomycin
  • some medicines for seizures like carbamazepine, phenobarbital, phenytoin, and primidone
  • thiopental
  • verapamil

What should I watch for while using this medicine?

Your condition will be closely monitored while you receive this medicine.

You may feel dizzy and lightheaded. To reduce the risk of dizzy or fainting spells, do not sit up or stand up quickly, especially if you are an older patient. Alcohol can make you more drowsy or dizzy. Avoid alcoholic drinks for at least 24 hours after you receive this medicine.

The effects of this medicine can last for several hours after use. It can affect your ability to drive or do anything that needs mental alertness. Do not attempt to drive yourself home if you have received this medicine for minor outpatient surgery.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • confusion
  • dizziness or lightheadedness
  • fast, irregular heartbeat
  • halluninations during recovery
  • numbness or tingling in the hands or feet
  • pain, redness, or swelling at site where injected
  • seizures

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • coughing
  • headache
  • hiccups
  • involuntary eye and muscle movements
  • loss of memory of events just before, during, and after use
  • nausea, vomiting
  • speech problems
  • tiredness
  • trouble sleeping or nightmares

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: June 25, 2009
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