Drugs A - Z

Methylene Blue Oral tablet

It is a dye that is used in certain diagnostic procedures.

Generic Name: methylene blue

Brand Names: Urolene Blue

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

METHYLENE BLUE (METH uh leen bloo) is a dye that is used in certain diagnostic procedures.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • cyanide poisoning
  • glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • kidney disease
  • an unusual or allergic reaction to methylene blue, phenothiazines, thiazide diuretics, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take after meals. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • bupropion
  • certain medicines for depression or anxiety
  • clomipramine
  • doxepin
  • duloxetine
  • fluoxetine
  • MAOIs like Marplan, Nardil, and Parnate
  • milnacipran
  • mirtazapine
  • rasagiline
  • selegiline
  • St. John's wort
  • trazodone
  • tryptophan

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • bladder irritation
  • fever

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • blue-green coloration of urine and stools
  • diarrhea
  • nausea, vomiting
  • skin discoloration

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: November 19, 2012
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