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Metformin Hydrochloride Oral solution

It is used to treat type 2 diabetes

Generic Name: metformin  |  Brand Name: Riomet

Brand Names: Metformin Hydrochloride ER, Glumetza, Riomet, Glucophage XR, Glucophage, Fortamet

There is an FDA Alert for this drug. Click here to view it.

  • Lactic acidosis rare but potentially fatal. Increased risk of lactic acidosis in patients with renal impairment, advanced age, metformin plasma concentrations >5 mcg/mL.
  • Generally has occurred in diabetic patients with severe renal insufficiency who frequently had concomitant medical and/or surgical problems and were receiving multiple drugs.
  • Periodically monitor renal function and use the minimum effective dosage. Withhold promptly in patients with any condition associated with hypoxemia, sepsis, or dehydration. Avoid use in patients with clinical or laboratory evidence of hepatic impairment. Discontinue therapy temporarily in patients undergoing surgery or receiving parenteral iodinated radiographic contrast media. Drugs that may affect renal function or alter metformin elimination should be used with caution.
  • Advise patients not to consume excessive amounts of alcohol.
  • If lactic acidosis occurs, discontinue metformin. Immediate hospitalization and treatment required.

What is this medicine?

METFORMIN (met FOR min) is used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise. This medicine can be used alone or with other medicines for diabetes.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • frequently drink alcohol-containing beverages
  • become easily dehydrated
  • heart attack
  • heart failure that is treated with medications
  • kidney disease
  • liver disease
  • polycystic ovary syndrome
  • serious infection or injury
  • vomiting
  • an unusual or allergic reaction to metformin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take with meals. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 10 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • dofetilide
  • gatifloxacin
  • certain contrast medicines given before X-rays, CT scans, MRI, or other procedures

This medicine may also interact with the following medications:

  • digoxin
  • diuretics
  • female hormones, like estrogens or progestins and birth control pills
  • isoniazid
  • medicines for blood pressure, heart disease, irregular heart beat
  • morphine
  • nicotinic acid
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • phenytoin
  • procainamide
  • quinidine
  • quinine
  • ranitidine
  • steroid medicines like prednisone or cortisone
  • stimulant medicines for attention disorders, weight loss, or to stay awake
  • thyroid medicines
  • trimethoprim
  • vancomycin

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

If you have low blood sugar, eat or drink something that has sugar. Make sure others know to get medical help quickly if you have serious symptoms of low blood sugar, like if you become unconscious or have a seizure.

If you need surgery or if you will need a procedure with contrast drugs, tell your doctor or health care professional that you are taking this medicine.

Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • feeling faint or lightheaded, falls
  • low blood sugar (ask your doctor or health care professional for a list of these symptoms)
  • muscle aches or pains
  • slow or irregular heartbeat
  • unusual stomach pain or discomfort
  • unusually tired or weak

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • headache
  • heartburn
  • metallic taste in mouth
  • nausea
  • stomach gas, upset


Last Updated: July 07, 2009
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