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Lomitapide Oral capsule

It is used in combination with diet and other medicines to lower blood cholesterol levels in patient... more

Generic Name:

What is this medicine?

LOMITAPIDE is used in combination with diet and other medicines to lower blood cholesterol levels in patients with a genetic disorder that results in high blood cholesterol levels.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

-if you often drink alcohol
-kidney disease
-liver disease
-an unusual or allergic reaction to lomitapide, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 2 hours after your evening meal. Do not take with food. Do not cut, crush or chew this medicine. Do not take with grapefruit juice. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, the normal dose should be taken at the usual time the next day. If you miss your dose for more than a week, contact your doctor or healthcare professional before restarting treatment.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

-aprepitant, fosaprepitant
-boceprevir
-calcium channel blockers like diltiazem and verapamil
-certain antibiotics like ciprofloxacin, clarithromycin, erythromycin and telithromycin
-certain antiviral medicines for HIV or AIDS
-certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, and voriconazole
-conivaptan
-crizotinib
-grapefruit juice
-imatinib
-nefazodone
This medicine may also interact with the following medications:

-acetaminophen
-ambrisentan
-bicalutamide
-birth control pills
-certain medicines for blood pressure, heart disease, irregular heart beat
-certain medicines for cholesterol like atorvastatin, lovastatin, simvastatin, cholestyramine, and colestipol
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for diabetes, like saxagliptin and sitagliptin
-certain medicines for stomach problems like cimetidine and ranitidine
-certain medicines that treat or prevent blood clots like warfarin, dabigatran, and ticagrelor
-cilostazol
-colchicine
-cyclosporine
-everolimus
-fexofenadine
-isoniazid
-isotretinoin
-lapatinib
-methotrexate
-nilotinib
-pazopanib
-sirolimus
-supplements like ginkgo biloba and goldenseal
-tamoxifen
-tetracycline
-topotecan
-zileuton

What should I watch for while using this medicine?

To help prevent stomach problems while taking this medicine, you should stay on a low-fat diet. This medicine makes it harder for some nutrients to get into your body. You should take Vitamin E and fatty acids each day while you are taking this medicine. Talk to your doctor or healthcare provider about how to add these to your diet.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

This medicine can cause liver injury. The risk of liver injury is increased in patients who drink alcohol while taking this medicine. Do not drink more than one alcoholic drink per day while taking this medicine.


Last Updated: January 08, 2013
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