Drugs A - Z

Lisdexamfetamine Dimesylate Oral capsule

It is used to treat attention-deficit hyperactivity disorder (ADHD)

Generic Name: lisdexamfetamine

Brand Names: Vyvanse

There is an FDA Alert for this drug. Click here to view it.

    Abuse Potential
  • Amphetamines have a high potential for abuse.
  • Administration of amphetamines for prolonged periods of time may lead to drug dependence.
  • Particular attention should be paid to the possibility of individuals obtaining amphetamines for nontherapeutic use or distribution to others, and the drugs should be prescribed or dispensed sparingly.
  • The possibility that family members may abuse the patient’s medication should be considered.

    Sudden Death and Serious Cardiovascular Events
  • Possible sudden death and serious cardiovascular events, particularly in individuals who abuse amphetamines. (See Sudden Death and Serious Cardiovascular Events under Cautions.)

What is this medicine?

LISDEXAMFETAMINE (lis DEX am fet a meen) is used to treat attention-deficit hyperactivity disorder (ADHD). Federal law prohibits giving this medicine to any person other than the person for whom it was prescribed. Do not share this medicine with anyone else.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • glaucoma
  • hardening or blockages of the arteries or heart blood vessels
  • heart disease or a heart defect
  • high blood pressure
  • history of alcohol or drug abuse
  • psychotic illness, depressed mood, or suicidal thoughts
  • seizure disorder
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • thyroid problems
  • Tourette's syndrome
  • an unusual or allergic reaction to lisdexamfetamine, other amphetamines, tartrazine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Swallow the capsules with a drink of water. You may open capsule and add to a glass of water, then drink right away. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not suddenly stop your medicine. You must gradually reduce the dose or you may feel withdrawal effects. Ask your doctor or health care professional for advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol
  • certain migraine headache medicines like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
  • lithium
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • melatonin
  • meperidine
  • other stimulant medications like dexmethylphenidate, methylphenidate, modafinil
  • pimozide
  • procarbazine

This medicine may also interact with the following medications:

  • acetazolamide
  • ammonium chloride
  • green tea
  • levodopa
  • linezolid
  • medicines for colds, sinus, and breathing difficulties
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for seizures
  • medicines for sleep during surgery
  • medicines for the heart or blood pressure
  • methenamine
  • norepinephrine
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • propoxyphene
  • sodium acid phosphate
  • sodium bicarbonate


Last Updated: June 24, 2009
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement
Advertisement
Advertisement