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Levomefolate Calcium Oral tablet

It is used together with medicines to manage depression and schizophrenia

Generic Name: l-methylfolate

Brand Names: Deplin, Zervalx

What is this medicine?

LEVOMEFOLATE is a medical food. It is used together with medicines to manage depression and schizophrenia.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • history of bipolar disorder
  • history of tumors in your intestines
  • vitamin B12 deficiency
  • an unusual or allergic reaction to levomefolate, folic acid, other B vitamins, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medical food by mouth with a glass of water. Follow the directions on your prescription label. You can take it with or without food. Take your doses at regular intervals. Do not stop taking your medicine unless your doctor tells you to.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • alcohol
  • birth control pills
  • capecitabine
  • certain antibiotics like pentamidine, pyrimethamine, and trimethoprim
  • cholestyramine
  • colchicine
  • colestipol
  • isotretinoin
  • medicines for seizures like carbamazepine, fosphenytoin, lamotrigine, phenytoin, phenobarbital, primidone, valproic acid, valproate
  • methotrexate
  • methylprednisone
  • nitrofurantoin
  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • pancreatic enzymes like pancrelipase and pancreatin
  • pyrimethamine
  • sulfasalazine
  • triamterene

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular check ups. Your doctor may order blood tests.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: October 27, 2010
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