Drugs A - Z

Imiquimod Topical cream

It cream is used to treat external genital or anal warts

Generic Name: imiquimod topical

Brand Names: Zyclara, Aldara

What is this medicine?

IMIQUIMOD (i mi KWI mod) cream is used to treat external genital or anal warts. It is also used to treat other skin conditions such as actinic keratosis and certain types of skin cancer.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • decreased immune function
  • an unusual or allergic reaction to imiquimod, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Apply just before bedtime. Wash your hands before and after use. Apply a thin layer of cream and massage gently into the affected areas until no longer visible. Do not use in the mouth, eyes or the vagina. Use this medicine only on the affected area as directed by your health care provider. Do not use for longer than prescribed. It is important not to use more medicine than prescribed. To do so may increase the chance of side effects.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other medicines on the treated area without asking your doctor or health care professional.

What should I watch for while using this medicine?

Visit your health care professional for regular checks on your progress.

Do not use this medicine until the skin has healed from any other drug (example: podofilox or podophyllin resin) or surgical skin treatment.

Females should receive regular pelvic exams while being treated for genital warts. Most patients see improvement within 4 weeks. It may take up to 16 weeks to see a full clearing of the warts. This medicine is not a cure. New warts may develop during or after treatment. Avoid sexual (genital, anal, oral) contact while the cream is on the skin. If warts are visible in the genital area, sexual contact should be avoided until the warts are treated. The use of latex condoms during sexual contact may reduce, but not entirely prevent, infecting others. This medicine may weaken condoms, diaphragms, cervical caps or other barrier devices and make them less effective as birth control. Do not cover the treated area with an airtight bandage. Cotton gauze dressings can be used. Cotton underwear can be worn after using this medicine on the genital or anal area.

Actinic keratoses that were not seen before may appear during treatment and may later go away. The treatment area and surrounding area may lighten or darken after treatment with this medicine. These skin color changes may be permanent in some patients.

If you experience a skin reaction at the treatment site that interferes or prevents you from doing any daily activity, contact your health care provider. You may need a rest period from treatment. Treatment may be restarted once the reaction has gotten better as recommended by your doctor or health care professional.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.


Last Updated: December 01, 2009
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