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Ibutilide Fumarate Solution for injection

This medicine can help your heart beat regularly

Generic Name: ibutilide

Brand Names: Corvert

There is an FDA Alert for this drug. Click here to view it.

  • May cause potentially fatal arrhythmias. Should be administered only by skilled personnel in a setting in which proper equipment (e.g., cardiac monitors, intracardiac pacing, cardioverter/defibrillator) and therapy for sustained VT are available during and after drug administration. (See Arrhythmogenic Effects under Cautions.)
  • Adequate anticoagulation recommended for patients with atrial fibrillation of more than 2–3 days’ duration.
  • Select patients carefully such that the expected benefits of conversion to sinus rhythm outweigh the immediate risks of ibutilide therapy. Use ibutilide when it is likely to offer an advantage compared with alternative management methods for atrial flutter or fibrillation. (See Supraventricular Tachyarrhythmias under Uses.)

What is this medicine?

IBUTILIDE is an antiarrhythmic agent. This medicine can help your heart beat regularly.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • liver disease
  • low blood magnesium levels
  • low blood potassium levels
  • other heart problems
  • an unusual or allergic reaction to ibutilide, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health-care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • amoxapine
  • arsenic trioxide
  • certain antibiotics like clarithromycin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, sparfloxacin, telithromycin, troleandomycin
  • cisapride
  • droperidol
  • haloperidol
  • hawthorn
  • levomethadyl
  • maprotiline
  • medicines to control heart rhythm
  • medicines to treat or prevent malaria like chloroquine or halofantrine
  • methadone
  • pentamidine
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • pimozide
  • ranolazine
  • sertindole
  • tricyclic antidepressants
  • vardenafil
  • ziprasidone

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • fast, irregular heartbeat
  • palpitations
  • slow heart rate

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • increased blood pressure
  • nausea

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: May 05, 2009
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