Drugs A - Z

Hydrocodone Bitartrate, Phenylephrine Hydrochloride Oral solution

It is used to treat the cough and congestion of colds and other respiratory infections

Generic Name: hydrocodone-phenylephrine  |  Brand Name: Nalex-DH

Brand Names: Tusdec-HC, Lortuss HC, Nalex-DH, Phenylephrine HD

What is this medicine?

HYDROCODONE; PHENYLEPHRINE (hye droe KOE done; fen il EF rin) is a cough suppressant with a decongestant. It is used to treat the cough and congestion of colds and other respiratory infections. This medicine will not treat an infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • drug abuse or addiction
  • heart disease
  • high blood pressure
  • high pressure around the brain
  • if you have taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • stomach or intestinal problems
  • thyroid disease
  • an unusual or allergic reaction to hydrocodone, phenylephrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Patients over 60 years old may have a stronger reaction to this medicine.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • alcohol
  • antihistamines for allergy, cough and cold
  • barbiturates like phenobarbital
  • medicines for chest pain, heart disease, high blood pressure, or heart rhythm problems
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • narcotic medicines (opiates) for pain
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • tramadol

What should I watch for while using this medicine?

Use exactly as directed by your doctor or health care professional. Do not take more than the recommended dose. You may develop tolerance to this medicine if you take it for a long time. Tolerance means that you will get less cough relief with time. Tell your doctor or health care professional if your symptoms do not improve or if they get worse.

Do not suddenly stop taking your medicine because you may develop a severe reaction.Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.


Last Updated: August 27, 2012
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement
Advertisement