Drugs A - Z
Narcotic Cough/Cold Preparations Oral syrup
Generic Name: guaifenesin/hydrocodone/pseudoephedrine | Brand Name: Poly-Tussin XP
What is this medicine?GUAIFENESIN; HYDROCODONE; PSEUDOEPHEDRINE (gwye FEN e sin; hye droe KOE done; soo doe e FED rin) is an expectorant, cough suppressant, and decongestant combination. It is used to treat the cough and congestion of colds and other respiratory infections. This medicine will not treat an infection.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- drug abuse or addiction
- constipation or other intestinal problems
- heart disease
- high blood pressure
- if you have taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
- lung or breathing disease, like asthma
- trouble passing urine
- an allergic or unusual reaction to codeine, hydrocodone, guaifenesin, pseudoephedrine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Take this medicine by mouth. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food.
Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.
Patients over 60 years old may have a stronger reaction and need a smaller dose.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
- ergot alkaloids like dihydroergotamine
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
- stimulant medicines for attention disorders, weight loss, or to stay awake
This medicine may also interact with the following medications:
- antihistamines for allergy, cough and cold
- barbiturates like phenobarbital
- certain heart medicines like metoprolol and methyldopa
- medicines for blood pressure
- medicines for depression, anxiety, or psychotic disturbances
- medicines for sleep
- muscle relaxants
- narcotic medicines (opiates) for pain
What should I watch for while using this medicine?Use exactly as directed by your doctor or health care professional. Do not take more than the recommended dose. You may develop tolerance to this medicine if you take it for a long time. Tolerance means that you will get less cough relief with time. Tell your doctor or health care professional if your symptoms do not improve or if they get worse.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a nonmedical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
Drink several glasses of water each day.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- anxiety, irritable, or excited
- breathing problems
- fast, irregular heartbeat
- feeling faint or lightheaded, falls
- high or low blood pressure
- trouble passing urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- stomach upset, nausea
- trouble sleeping
Where should I keep my medicine?Keep out of the reach of children. This drug can be abused. Keep this medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and is against the law.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).
Throw away any unused medicine after the expiration date. Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.