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Fluphenazine Hydrochloride Oral tablet

It helps to treat disordered thoughts and some other emotional, nervous, and mental problems.

Generic Name: fluphenazine

Brand Names: Permitil, Prolixin Enanthate, Prolixin

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

FLUPHENAZINE (floo FEN a zeen) helps to treat disordered thoughts and some other emotional, nervous, and mental problems.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • blood disorders or disease
  • dementia
  • head injury
  • heart disease
  • liver disease
  • Parkinson's disease
  • Reye's syndrome
  • uncontrollable movement disorder
  • an unusual or allergic reaction to fluphenazine, tartrazine dye, other medicines foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 5 years for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • amoxapine
  • certain antibiotics like gatifloxacin and sparfloxacin
  • cisapride
  • clozapine
  • dofetilide
  • droperidol
  • ephedrine
  • certain medicines for mental depression like escitalopram, fluoxetine, paroxetine, sertraline
  • ibutilide
  • levomethadyl
  • maprotiline
  • other phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, and thioridazine
  • pimozide
  • pindolol
  • propranolol
  • risperidone
  • sotalol
  • trimethobenzamide
  • ziprasidone

This medicine may also interact with the following medications:

  • atropine
  • some medications for high blood pressure or heart problems

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.

This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.


Last Updated: May 07, 2013
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