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Factor VIIa (Recomb)(Murine)(Bovine)(Hamster) Solution for injection

It helps to prevent or control bleeding in patients with hemophilia A or hemophilia B who have clott... more

Generic Name: coagulation factor VIIa

Brand Names: NovoSeven, NovoSeven RT

There is an FDA Alert for this drug. Click here to view it.

  • Risk of serious arterial and venous thromboembolic adverse events, particularly when factor VIIa (recombinant) is used outside FDA-labeled indications. (See Thromboembolic Events under Cautions.)
  • Both fatal and nonfatal thromboembolic events have been reported in clinical studies and during postmarketing experience.
  • Discuss risk of thromboembolism with patient. Monitor for signs and symptoms of coagulation system activation and thrombosis during therapy.

What is this medicine?

FACTOR VIIa, RECOMBINANT (fak tir VIIa, ree kom bi nant) helps to prevent or control bleeding in patients with hemophilia A or hemophilia B who have clotting factor inhibitors. This medicine may also be used to treat bleeding in patients with factor VII deficiency or in select patients who have other types of bleeding problems.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • hardening of the arteries
  • other coagulation problems
  • thrombosis
  • an unusual or allergic reaction to human or animal (cow, hamster, or mouse) protein, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Let the powder and solution warm to room temperature before use. Follow mixing directions carefully to avoid foaming. Swirl but do not shake the solution. Throw away any unused portion. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

Try not to miss doses. Ask your doctor or health care professional for instructions if you miss a dose.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • warfarin

This medicine may also interact with the following medications:

  • factor IX products

What should I watch for while using this medicine?

If you are a hemophilia patient, carry an identification card with you at all times. The card should have your name, the name and dose of your medication(s), the name and phone number of your doctor or health care professional, and a contact person in case of emergency.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • an allergic reaction including difficulty breathing, wheezing, hives, skin rash, itching, tightness of the chest
  • bruising or continued bleeding
  • cough or other signs of infection
  • fever or chills
  • pain, redness or swelling at the injection site
  • swelling of legs

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • vomiting

Where should I keep my medicine?

Keep out of the reach of children.

If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: April 27, 2009
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Coagulation factor VIIa

 
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