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Exenatide Suspension for injection, Extended Release

It is used to improve blood sugar control in adults with type 2 diabetes

Generic Name: Bydureon

What is this medicine?

EXENATIDE (ex EN a tide) is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • endocrine tumors (MEN 2) or if someone in your family had these tumors
  • history of pancreatitis
  • kidney disease or if you are on dialysis
  • stomach problems
  • thyroid cancer or if someone in your family had thyroid cancer
  • an unusual or allergic reaction to exenatide, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection under the skin of your upper leg, stomach area, or upper arm. It is usually given once every week (every 7 days). You will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can, provided your next usual scheduled dose is due at least 3 days later. If you miss a dose and your next usual scheduled dose is due 1 or 2 days later, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses. If you have questions about a missed dose, contact your health care provider for advice.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • gatifloxacin

This medicine may also interact with the following medications:

  • acetaminophen
  • birth control pills
  • digoxin
  • lisinopril
  • lovastatin
  • sulfonylureas
  • warfarin

Many medications may cause changes in blood sugar, these include:

  • alcohol containing beverages
  • aspirin and aspirin-like drugs
  • chloramphenicol
  • chromium
  • diuretics
  • female hormones, such as estrogens or progestins, birth control pills
  • heart medicines
  • isoniazid
  • male hormones or anabolic steroids
  • medications for weight loss
  • medicines for allergies, asthma, cold, or cough
  • medicines for mental problems
  • medicines called MAO inhibitors - Nardil, Parnate, Marplan, Eldepryl
  • niacin
  • NSAIDS, such as ibuprofen
  • pentamidine
  • phenytoin
  • probenecid
  • quinolone antibiotics such as ciprofloxacin, levofloxacin, ofloxacin
  • some herbal dietary supplements
  • steroid medicines such as prednisone or cortisone
  • thyroid hormones

Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:

  • beta-blockers, often used for high blood pressure or heart problems (examples include atenolol, metoprolol, propranolol)
  • clonidine
  • guanethidine
  • reserpine


Last Updated: March 09, 2012
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