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Edetate Disodium Solution for injection

It is used to treat calcium overload

Generic Name: edetate disodium

Brand Names: Endrate, Edetate Disodium Dihydrate, Disotate

What is this medicine?

EDETATE DISODIUM, EDTA (ED uh teyt di SOE dee um) EDTA binds with calcium and some heavy metals in the body. It is used to treat calcium overload. It is also used to treat irregular heart beats caused by too much digitalis (digoxin or digitoxin).

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • heart disease or failure
  • kidney disease or trouble making urine
  • low levels of calcium or potassium in the blood
  • an unusual or allergic reaction to edetate disodium, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

  • calcium
  • digoxin
  • insulin
  • magnesium

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • cloudy or dark urine
  • fast, irregular heartbeat
  • feeling faint or lightheaded, falls
  • fever or chills
  • irritation, pain at site where injected
  • low blood pressure
  • muscle cramps, pain, stiffness
  • numb, tingling pain
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • trouble passing urine or change in the amount of urine
  • unusually tired or weak

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • headache
  • nausea, vomiting
  • stomach pain

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: April 21, 2009
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