Drugs A - Z

Dolasetron Mesylate Monohydrate Solution for injection

It is used to treat and prevent nausea and vomiting after surgery.

Generic Name: dolasetron  |  Brand Name: Anzemet

Brand Names: Anzemet

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

DOLASETRON (dol A se tron) is used to treat and prevent nausea and vomiting after surgery.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart disease
  • history of irregular heartbeat
  • kidney disease
  • low levels of magnesium or potassium in the blood
  • an unusual or allergic reaction to dolasetron, granisetron, ondansetron, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health-care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this medicine may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • arsenic trioxide
  • certain antipsychotics like haloperidol, thioridazine, ziprasodone
  • certain medicines for chemotherapy like daunorubicin, epirubicin, idarubicin
  • certain medicines for irregular heart beat like amiodarone, disopyramide, dofetilide, ibutilide, procainamide, propafenone, quinidine, sotalol
  • certain medicines used for nausea like chlorpromazine, droperidol
  • certain medicines used to treat infections like chloroquine, clarithromycin, erythromycin, pentamidine
  • cisapride
  • dextromethorphan; quinidine
  • dronedarone
  • flecainide
  • methadone

This medicine may also interact with the following medications:

  • antiviral medicines for HIV or AIDS
  • atenolol
  • beta-blockers like propranolol
  • calcium channel blockers like diltiazem and verapamil
  • cimetidine
  • digoxin
  • diuretics
  • rifampin

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • chest tightness
  • dizziness
  • fast or irregular heartbeat
  • feeling faint or lightheaded, falls
  • fever and chills
  • swelling of the feet or hands

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation or diarrhea
  • headache

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: September 29, 2011
Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement
Advertisement