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Estradiol Valerate Oral tablets, Dienogest Oral tablets

This medicine combines two types of female hormones, an estrogen and a progestin

Generic Name: Natazia

What is this medicine?

DIENOGEST; ESTRADIOL VALERATE is an oral contraceptive (birth control pill). This medicine combines two types of female hormones, an estrogen and a progestin. It is used to prevent ovulation and pregnancy. This medicine is also used to treat heavy menstruation (monthly periods) in women who also want to prevent pregnancy.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • abnormal vaginal bleeding
  • blood vessel disease or blood clots
  • breast, cervical, endometrial, ovarian, liver, or uterine cancer
  • diabetes
  • gallbladder disease
  • heart disease or recent heart attack
  • high blood pressure
  • high cholesterol
  • kidney disease
  • liver disease or liver cancer
  • mental illness
  • migraine headaches
  • stroke
  • swelling of the face or tongue
  • systemic lupus erythematosus (SLE)
  • tobacco smoker
  • an unusual or allergic reaction to estrogens, progestins, or other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take this medicine at the same time each day and in the order directed on the package. Do not take your medicine more often than directed.

A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. This medicine has been used in adolescents who have started having menstrual periods.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, refer to the patient information sheet you received with your medicine for direction. If you miss more than one pill, this medicine may not be as effective and you may need to use another form of birth control.

What may interact with this medicine?

  • antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, griseofulvin, and possibly penicillins, tetracyclines, or macrolides like erythromycin
  • barbiturate medicines, such as phenobarbital
  • bosentan
  • carbamazepine
  • certain antidepressants
  • certain medicines for blood pressure like diltiazem, verapamil
  • certain medicines for fungal infections like ketoconazole and itraconazole
  • cimetidine
  • felbamate
  • grapefruit juice
  • ketoconazole
  • lamotrigine
  • oxcarbazepine
  • phenytoin
  • ritonavir or other medicines for HIV infection or AIDS
  • soy isoflavones supplements
  • St. John's wort
  • topiramate
  • warfarin


Last Updated: March 19, 2012
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