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Antitussive with Decongestant and Expectorant Oral Capsule

It is used to provide relief from cough and congestion

Generic Name: dextromethorphan/guaifenesin/pseudoephedrine  |  Brand Name: Z-Cof DM

What is this medicine?

DEXTROMETHORPHAN; GUAIFENESIN; PSEUDOEPHEDRINE (dex troe meth OR fan, gwye FEN e sin; soo doe e FED rin) is a combination of a cough suppressant, an expectorant, and a decongestant. It used to provide relief from cough and congestion. This medicine will not treat an infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • difficulty passing urine
  • glaucoma
  • high blood pressure, heart disease
  • liver disease
  • an unusual or allergic reaction to dextromethorphan, guaifenesin, pseudoephedrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not crush or chew. If this medicine upsets your stomach, take with food or milk. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 60 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • procarbazine
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • caffeine
  • digoxin
  • furazolidone
  • linezolid
  • maprotiline
  • mecamylamine
  • medicines for blood pressure
  • medicines for cold, cough or allergy
  • reserpine
  • some medicines for Parkinson's disease
  • St. John's wort
  • theophylline

What should I watch for while using this medicine?

Use as directed by your doctor or health care professional. Do not take more than the recommended dose. Tell your doctor if your symptoms do not improve within 5 days or if they get worse. If you have trouble falling asleep at night, take the last dose of the day at least a few hours before bedtime.

Drink water as instructed while you are taking this medicine to help loosen mucus.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • difficulty passing urine
  • fast or irregular heartbeat
  • fear, anxiety, restless, tremor
  • fever
  • hallucinations
  • high blood pressure
  • seizure
  • trouble breathing
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • drowsiness
  • headache
  • loss of appetite
  • stomach upset, nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: April 07, 2009
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Dextromethorphan/guaifenesin/pseudoephedrine

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