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Dextroamphetamine Sulfate Oral capsule, extended release

It is used to treat attention-deficit hyperactivity disorder (ADHD)

Generic Name: dextroamphetamine

Brand Names: Dexedrine Spansule, Dextrostat, Dextroamphetamine Sulfate, Dexedrine

There is an FDA Alert for this drug. Click here to view it.

    Abuse Potential
  • Amphetamines have a high potential for abuse.
  • Administration of amphetamines for prolonged periods of time may lead to drug dependence.
  • Particular attention should be paid to the possibility of individuals obtaining amphetamines for nontherapeutic use or distribution to others, and the drugs should be prescribed or dispensed sparingly.
  • The possibility that family members may abuse the patient’s medication should be considered.

    Sudden Death and Serious Cardiovascular Events
  • Possible sudden death and serious cardiovascular events, particularly in individuals who abuse amphetamines. (See Sudden Death and Serious Cardiovascular Events under Cautions.)

What is this medicine?

DEXTROAMPHETAMINE (dex troe am FET a meen) is used to treat attention-deficit hyperactivity disorder (ADHD). It may also be used for narcolepsy. Federal law prohibits giving this medicine to any person other than the person for whom it was prescribed. Do not share this medicine with anyone else.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • glaucoma
  • hardening or blockages of the arteries or heart blood vessels
  • heart disease or a heart defect
  • high blood pressure
  • history of a drug or alcohol abuse problem
  • psychotic illness, depressed mood, or suicidal thoughts
  • seizures
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • thyroid disease
  • Tourette's syndrome
  • an unusual or allergic reaction to dextroamphetamine, other amphetamines, tartrazine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol
  • certain migraine headache medicines like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
  • lithium
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • melatonin
  • meperidine
  • other stimulant medicines for attention disorders, weight loss, or to stay awake
  • pimozide
  • procarbazine

This medicine may also interact with the following medications:

  • acetazolamide
  • ammonium chloride
  • ascorbic acid
  • glutamic acid
  • medicines for blood pressure, heart disease, irregular heart beat
  • medicines for colds, sinus, and breathing difficulties
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for seizures like carbamazepine, phenobarbital, phenytoin
  • methenamine
  • norepinephrine
  • propoxyphene
  • sodium acid phosphate
  • sodium bicarbonate


Last Updated: April 07, 2009
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