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Dexrazoxane Hydrochloride Solution for injection

It is used to protect against damage caused by certain chemotherapy.

Generic Name: dexrazoxane  |  Brand Name: Zinecard

Brand Names: Totect, Zinecard

What is this medicine?

DEXRAZOXANE (dex ray ZOX ane) is used to protect against damage caused by certain chemotherapy.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bone marrow suppression
  • heart disease
  • kidney disease
  • an unusual or allergic reaction to dexrazoxane, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection or infusion into a vein. It is given by a health care professional in a hospital or clinic setting. This medicine is given just before you are given your chemotherapy medicine.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Interactions are not expected.

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

This medicine may increase your risk of getting an infection. Stay away from people who are sick and anyone who has recently had a vaccine. Call your doctor or health care professional for advice if you get a fever, chills, or sore throat. Do not treat yourself.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • fever, chills, or sore throat
  • mouth sores
  • pain at site where injected
  • unusual bleeding or bruising
  • unusually tired or weak
  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • confusion
  • depression
  • diarrhea
  • hair loss
  • nausea

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: April 09, 2009
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