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Cyanocobalamin (Vitamin B12) Solution for injection

Vitamin B12 is used in the growth of healthy blood cells, nerve cells, and proteins in the body

Generic Name: cyanocobalamin injection  |  Brand Name: Crystamine

Brand Names: Depo-Cobolin, Crystamine, Sytobex, Cyanoject

What is this medicine?

CYANOCOBALAMIN (sye an oh koe BAL a min) is a man made form of vitamin B12. Vitamin B12 is used in the growth of healthy blood cells, nerve cells, and proteins in the body. It also helps with the metabolism of fats and carbohydrates. This medicine is used to treat people who can not absorb vitamin B12.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • kidney disease
  • Leber's disease
  • megaloblastic anemia
  • an unusual or allergic reaction to cyanocobalamin, cobalt, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is injected into a muscle or deeply under the skin. It is usually given by a health care professional in a clinic or doctor's office. However, your doctor may teach you how to inject yourself. Follow all instructions.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you are given your dose at a clinic or doctor's office, call to reschedule your appointment. If you give your own injections and you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • colchicine
  • heavy alcohol intake

What should I watch for while using this medicine?

Visit your doctor or health care professional regularly. You may need blood work done while you are taking this medicine.

You may need to follow a special diet. Talk to your doctor. Limit your alcohol intake and avoid smoking to get the best benefit.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • blue tint to skin
  • chest tightness, pain
  • difficulty breathing, wheezing
  • dizziness
  • red, swollen painful area on the leg

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • headache

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 85 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: March 30, 2009
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