Drugs A - Z

Clofazimine Oral capsule

It is used to treat leprosy

Generic Name: clofazimine

Brand Names: Lamprene

What is this medicine?

CLOFAZIMINE (kloe FA zi meen) is an anti-infective medicine. It is used to treat leprosy.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • wear contact lenses
  • diarrhea
  • stomach problems, pain or bleeding
  • an unusual or allergic reaction to clofazimine, other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take with meals. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • dapsone

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

This medicine can color your skin from pink or red to brownish-black. It will also discolor your sweat, tears, urine, and stool. It may stain soft contact lenses. The darker skin color will go away. It may take months to years to fade after you stop taking this medicine. Talk to your doctor or health care professional about this if it causes you concern or makes you feel depressed.

Your skin may get dry and scaly. Applying oil may help.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • black, tarry stools
  • burning pain in the abdomen
  • changes in vision
  • constipation, diarrhea
  • depression
  • dry, burning or itching eyes
  • fever
  • loss of appetite
  • nausea, vomiting
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • discoloration of skin, tears, saliva, sweat, urine, or stools
  • dizzy, drowsy, fatigue
  • dry, scaly skin
  • skin rash, itching
  • stomach upset

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature below 30 degrees C (86 degrees F). Protect from moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: March 23, 2009
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