Drugs A - Z
Bupropion Hydrochloride Oral tablet, 24 hour [Depression/Mood Disorders]
Generic Name: buPROPion | Brand Name: Wellbutrin
What is this medicine?BUPROPION (byoo PROE pee on) is used to treat depression.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- an eating disorder, such as anorexia or bulimia
- bipolar disorder or psychosis
- diabetes or high blood sugar, treated with medication
- head injury or brain tumor
- heart disease, previous heart attack, or irregular heart beat
- high blood pressure
- kidney or liver disease
- seizures (convulsions)
- suicidal thoughts or a previous suicide attempt
- Tourette's syndrome
- weight loss
- an unusual or allergic reaction to bupropion, other medicines, foods, dyes, or preservatives
- pregnant or trying to become pregnant
How should I use this medicine?Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not crush, chew, or cut these tablets. This medicine is taken once daily at the same time each day. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?If you miss a dose, skip the missed dose and take your next tablet at the regular time. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
- other medicines that contain bupropion like Zyban
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
- levodopa or combination drugs containing levodopa
- medicines for mental depression, emotional, or psychotic disturbances
- medicines or herbal products for weight control or appetite
- some medicines for heart rhythm or blood pressure
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?Visit your doctor or health care professional for regular checks on your progress. You may have to take this medicine for several days before you start to feel better. If you have been taking this medicine for some time, do not suddenly stop taking it. Your doctor or health care professional may want you to gradually reduce the dose.
Patients and their families should watch for depression or thoughts of suicide that gets worse. Also watch for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your doctor.
Alcohol may increase dizziness or drowsiness. Avoid alcoholic drinks while taking this medicine. Drinking large amounts of alcoholic beverages, using sleeping or anxiety medicines, or quickly stopping the use of these agents while taking this medicine may increase your risk for a seizure.
You may get dizzy or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
Do not treat yourself for coughs, colds, or allergies without asking your doctor or health care professional. Some ingredients may increase possible side effects.
The tablet shell for some brands of this medicine does not dissolve. This is normal. The tablet shell may appear whole in the stool. This is not a cause for concern.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- changes in vision
- fast or irregular heartbeat
- increased blood pressure
- redness, blistering, peeling or loosening of the skin, including inside the mouth
- suicidal thoughts or other mood changes
- unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- change in sex drive or performance
- loss of appetite
- weight loss
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.