Drugs A - Z
Buprenorphine Hydrochloride Sublingual tablet
Generic Name: buprenorphine | Brand Name: Subutex
What is this medicine?BUPRENORPHINE; NALOXONE (byoo pre NOR feen; nal OX one) is used to treat certain types of drug dependence.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- brain tumor
- drink more than 3 alcohol-containing drinks per day
- head injury
- heart disease
- kidney disease
- liver disease
- lung disease such as asthma or COPD
- an unusual or allergic reaction to buprenorphine, naloxone, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Place this medicine under the tongue and let it dissolve. Several minutes will be needed to let it fully dissolve. Follow the directions on the prescription label. Leave this medicine in the sealed foil pack until you are ready to use it. If your dose requires you to take more than 2 tablets at once, either place all the tablets at once under the tongue, or if you cannot fit more than 2 tablets comfortably, place 2 tablets at a time under the tongue. Either way, you should hold the tablets under the tongue until they completely dissolve. Do not swallow or chew this medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 16 years of age for selected conditions, precautions do apply.
Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
- antibiotics like erythromycin and clarithromycin
- antihistamines for allergy, cough and cold
- barbiturates like phenobarbital
- general anesthetics
- medicines for depression, anxiety, or psychotic disturbances
- medicines for fungal infections like fluconazole, itraconazole, ketoconazole, and voriconazole
- medicines for sleep
- medicines used to treat HIV infection or AIDS like ritonavir, saquinavir, and indinavir
- muscle relaxants
- narcotic medicines (opiates) for pain
- phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
- rifampin or rifampicin
What should I watch for while using this medicine?Do not stop taking except on your doctor's advice. You may develop a severe reaction. Your doctor will tell you how much medicine to take.
Wear a medical identification bracelet or chain to say that you are taking this medicine. Emergency personnel will need to know that you are taking this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
You will likely have your blood checked before you start taking this medicine.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- anxiety, irritability, nervousness or restlessness
- breathing problems
- cold, clammy skin or sweating
- fainting spells
- severe stomach pain or vomiting
- yellowing of the skin or the whites of the eyes
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
Where should I keep my medicine?Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).
Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages. Flush any unused medicines down the toilet. Do not use the medicine after the expiration date. Follow the directions in the MedGuide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.